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Rimcazole dihydrochloride
CAS No. 75859-03-9
Rimcazole dihydrochloride( —— )
Catalog No. M33914 CAS No. 75859-03-9
Rimcazole dihydrochloride is the hydrochloride salt of Rimcazole, a σ receptor antagonist. Rimcazole dihydrochloride also binds to dopamine transporter proteins and inhibits dopamine uptake.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 58 | In Stock |
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| 5MG | 85 | In Stock |
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| 10MG | 140 | In Stock |
|
| 25MG | 296 | In Stock |
|
| 50MG | 480 | In Stock |
|
| 100MG | 683 | In Stock |
|
| 500MG | 1422 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameRimcazole dihydrochloride
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NoteResearch use only, not for human use.
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Brief DescriptionRimcazole dihydrochloride is the hydrochloride salt of Rimcazole, a σ receptor antagonist. Rimcazole dihydrochloride also binds to dopamine transporter proteins and inhibits dopamine uptake.
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DescriptionRimcazole (BW 234U) dihydrochloride is a carbazole derivative that acts in part as a sigma (σ) receptor antagonist. Rimcazole dihydrochloride also binds with moderate affinity to the dopamine transporter and inhibit dopamine uptake. Rimcazole dihydrochloride can reduce locomotor activity and sensitization. Rimcazole dihydrochloride also can be used for the research of cancer.
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In VitroWestern Blot AnalysisCell Line:HCT-116p53+/+ cells Concentration:50 μM Incubation Time:1, 2, 3, 5, 6, 24 hours Result:Accumulation of HIF-1α protein, maximal at 6?h.No change in p53 protein levels.HIF-1α protein levels returned to normal steady-state levels within 24?h.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number75859-03-9
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Formula Weight357.92
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Molecular FormulaC21H28ClN3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 12.5 mg/mL (31.70 mM; Ultrasonic (<60°C); )H2O : < 0.1 mg/mL (insoluble)
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SMILESCl.Cl.C[C@H]1CN(CCCn2c3ccccc3c3ccccc23)C[C@@H](C)N1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gilmore DL, et, al. Review of the pharmacological and clinical profile of rimcazole. CNS Drug Rev. Spring 2004;10(1):1-22.?
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